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Study of the Hemispheric Specialization for Language in Subjects With Neuropsychiatric Disorders Compared to Control Subjects | Clinical Trials | Clareo Health

COMPLETEDNA

Study of the Hemispheric Specialization for Language in Subjects With Neuropsychiatric Disorders Compared to Control Subjects

NCT02523742•University Hospital, Caen

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Summary

Recently, we have shown functional resonance imaging (fMRI) that variations in signal induced by a language task were significantly lower in a semantic region of the left hemisphere (comprised of that part pars triangularis of the inferior frontal gyrus and the temporal gyri medium and angular) in schizophrenic patients compared with controls matched for age, sex, level of education and handedness. Investigators wish to test the hypothesis that functional modification of the hemispherical specialization is specific language and also specific for schizophrenia.

Eligibility

Age

18 - 65 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•patients under 65 years
•Schizophrenics, bipolar or schizoaffective (DSM IV)
•Patients who signed informed consent

Exclusion Criteria

•Women with childbearing potential without effective contraception or positive pregnancy test.
•Contra-indications to fMRI

Key Dates

Start Date

November 1, 2005

Primary Completion Date

November 19, 2013

Completion Date

April 23, 2015

Last Updated

September 1, 2020

Enrollment

152

ACTUAL participants

Conditions

Neuropsychiatric Disorders

Interventions

IMRf

DEVICE

language task and a reference task (rest and Tamil)

OTHER

Reference Measurements of the Neuronal Integration Window and Anatomical and Functional MRI (Magnetic Resonance Imaging)

NCT07453108

Neuropsychiatric Disorders

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: September 1, 2020Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

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