Clinical Trial Assessing the Value of an Antibiotic Protocol Guided by Serum Procalcitonin in Acute Exacerbations of Chronic Obstructive Pulmonary Disease in Intensive Care
Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University Hospital, Caen
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
patients over 18 years
Documented or suspected clinically COPD according to the criteria of GOLD
In acute exacerbation
Suspect of lower respiratory tract infection
With or without pulmonary criteria defined as the presence of a radiological infiltrates consistent with an infectious site and associated with one or more of the following items: dyspnea, cough, sputum, fever above 38 ° C, fireplace clinical auscultation, higher leukocytosis at 10,000 / mm³ or leukopenia below 4000 / mm³
Admitted to the hospital for less than 48 hours
ICU Admission
Informed Consent signed by the patient or his representative
You may not be if
Other than acute exacerbation etiology with or without pulmonary disease as suspected cause of ICU admission
Patient immunocompromised neutropenia neutrophil count below 500 / mm³ secondary to chemotherapy, corticosteroids greater than 0.5 mg / kg / day for more than 10 days, HIV seropositivity
Severe Acute Asthma
Moribund patient or a disease with an estimated survival time of less than three months
Therapeutic limitation Existence
minor patient or under guardianship or custody
Pregnant woman
Refusal to participate in the study
The inclusion of the subject in another biomedical research protocol in progress or for less than 30 days
Clareo Health | Clinical Trial Assessing the Value of an Antibiotic Protocol Guided by Serum Procalcitonin in Acute Exacerbations of Chronic Obstructive Pulmonary Disease in Intensive Care