Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Avid Radiopharmaceuticals
Age
18–55
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
TBI Subjects
TBI Subjects
Subjects that have consented and are currently enrolled in either Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI), Evaluation, Pathogenesis, and Outcome of Subjects with or Suspected Traumatic Brain Injury Protocol Number: CNS: 10-N-N122, or Evaluation and Diagnosis of Potential Research Subjects with Traumatic Brain Injury (TBI): Protocol Number: 11-N-0084
History of having sustained a TBI \< 6 weeks prior to enrollment
Can tolerate PET and MRI scan procedures
Control Subjects
MMSE ≥ 28
No significant history of cognitive impairment
No prior history of TBI
Can tolerate PET and MRI scan procedures
You may not be if
Have behavior dysfunction that is likely to interfere with imaging
Are claustrophobic or otherwise unable to tolerate the imaging procedure
Have current clinically significant cardiovascular disease, or clinically significant abnormalities on screening ECG
A history of additional risk factors for Torsades de Pointes (TdP) or are taking drugs that are known to cause QT-prolongation
Have a current clinically significant infectious disease, endocrine or metabolic disease, pulmonary, renal or hepatic impairment, or cancer
Are females of childbearing potential who are not surgically sterile, not refraining from sexual activity or not using reliable methods of contraception
Have had a non-study related radiopharmaceutical imaging or treatment procedure within 7 days prior to the 18F-AV-1451 imaging session
Have current alcohol dependence or alcohol dependence within the past 1 year
Are currently participating in another interventional clinical trial
Have evidence of a penetrating brain injury
Have participated in contact sports in college or after high school age
