Phase 1, Febuxostat XR Relative Bioavailability Study

The drug being tested is this study is febuxostat XR. Four different formulations of febuxostat XR are being tested to see how the drug moves through the body. This study will look at safety and side effects in people who take febuxostat XR. This cross-over study will enroll approximately 78 patients. Participants will be randomly assigned to 1of 4 sequences which will determine the order of the 4 treatments received: * Febuxostat XR 80 mg capsule Formulation 1 * Febuxostat XR 80 mg capsule Formulation 2 * Febuxostat XR 80 mg capsule Formulation 3 * Febuxostat XR 80 mg capsule Formulation 4 Participants will take 1 dose on Day 1 with a washout period between each period. This single-center trial will be conducted in the United States. The overall time to participate in this study is up to 80 days. Participants will make multiple visits to the clinic including a period of confinement, and will be contacted by telephone 30 days after last dose of study drug for a follow-up assessment.