Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Centre Hospitalier Universitaire de Nice
Age
55–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age 55 years or more
30 or more pack-years of cigarette smoking history
Former smokers: quit smoking within the previous 15 years
Signed informed consent form
Presence of COPD
Affiliation to the French social security system
You may not be if
Chest CT examination in the 12 months prior to eligibility assessment(1)
Treatment for, or evidence of, any cancer other than skin basocellular carcinoma in the 5 years prior to eligibility assessment
Pneumonia or acute respiratory infection treated with antibiotics in the 12 weeks prior to eligibility assessment
Unexplained weight loss of more than 15 10%pounds in the 12 months prior to eligibility assessment
Recent hemoptysis
History of lung volume reduction with coils, glue or valves°
Metallic implants or devices in the chest or back, such as pacemakers or Harrington fixation rods
Participation in another cancer screening trial
Participation in a cancer prevention study, other than a smoking cessation study
Vulnerable persons: adults under guardianship, adults under trusteeship or persons deprived of their liberty, patients under 18 years old
Medical and/or psychiatric problems of sufficient severity to limit full compliance with the study or expose patients to undue risk
1. Many COPD patients will have had a previous chest CT examination. This has become common in medical practice, especially in patients with chronic lung diseases such as COPD patients. Including such patients would introduce huge bias in the study by artificially focusing on rapidly growing cancers. Redoing a CT in a screening intend in a patient who recently underwent this investigation would also unnecessarily enhance irradiation in these patients. It should be note that in the NLST trial "previous chest CT (≤ 18 months)" was a key exclusion criterion \[NLST Radiology 2011\].
