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Non-invasive Positive Pressure (NPPV ) for Severe Stable Chronic Obstructive Pulmonary Disease

Non-invasive Positive Pressure Ventilation for the Treatment of Severe Stable Chronic Obstructive Pulmonary Disease

NCT02499718•Guangzhou Institute of Respiratory Disease

Summary

Assessment of the effect and safety of noninvasive positive pressure ventilation for severe stable chronic obstructive pulmonary disease

Eligibility

Age

40 - 80 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•clinically stable, hypercapnic GOLD stage IV COPD, aged 18 years or older, baseline arterial carbon dioxide pressure (PaCO2) of 6.7 kPa (50 mmHg) or higher and a pH higher than 7·35, measured after at least 1 h rest in a sitting position.

Exclusion Criteria

•thorax or the lung other than COPD
•No smoking or Cigarette≤10/day
•obesity with a bodymass index (BMI) ≥40 kg/m²
•malignant co-morbidities,severe heart failure (New York Heart Association stage IV),unstable angina, and severe arrhythmias.

Locations (1)

Guangzhou Institute of Respiratory Disease

Guangzhou, Guangdong, China

Key Dates

Start Date

January 1, 2014

Primary Completion Date

December 1, 2016

Completion Date

December 1, 2016

Last Updated

July 16, 2015

Enrollment

368

ESTIMATED participants

Conditions

Chronic Obstructive Pulmonary DiseaseHypercapnic Respiratory Failure

Interventions

BiPAP mode

DEVICE

Contacts

Zhou LuQian, Doctor

CONTACT

+86-15622236759 zhlx09@163.com

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: July 16, 2015Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

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Non-invasive Positive Pressure (NPPV ) for Severe Stable Chronic Obstructive Pulmonary Disease

Inclusion Criteria

Exclusion Criteria

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