Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Hôpital de Verdun
Patients presenting to the participant Emergency Departments (ED) with a diagnosis of AECOPD and who receive at least one dose of albuterol, will be randomized to receive either placebo or one dose of MgSO4 2g IV. Security and efficacy outcomes will be measured.
Age
35–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Current or previous smoking for at least 10 pack-years
Confirmed COPD :
1. reported by the patient if already diagnosed in the past by a pulmonary disease specialist or on the basis of respiratory function tests; or
2. new diagnosis in the ED, with confirmatory pulmonary tests showing Forced Expiratory Volume (FEV1) / Forced Vital Capacity (FVC) ratio \< 70% and FEV1\< 80%
Patient requires at least one dose of albuterol (salbutamol).
You may not be if
Dialysis patients
Severe kidney disease, known or suspected to have a creatine clearance \< 15.
Metastatic neoplasm
Patients who received IV MgSO4 in the last week.
Hypotension, defined as systolic blood pressure less than 90.
Clareo Health | Magnesium Sulfate to Prevent Hospitalisation of Acute Exacerbations of Chronic Obstructive Pulmonary Disease
