History of weight loss surgery or active participation in weight loss program

Major medical problem (e.g., diabetes, cancer)

Current use of weight loss medications or other medications known to alter appetite

Pregnancy or menopause

MRI contraindication (i.e., implanted metal, claustrophobia)

Lifetime eating disorder

Current smoking

Current heavy alcohol use (≥2 drinks per day for females and ≥ 3 drinks per day for males)

Self-reported weight \>330 pounds at time of phone screening. MRI cannot accommodate all shapes or weights. Inability to have MRI does not exclude subject from participating in other study procedures.

BMI \< 18.5 or \> 45 kg/m\^2

Allergies to study foods or inability to taste

Twins were raised apart

Brain Regulation of Appetite in Twins

What this study is about