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COMPLETEDPhase 1NCT02477514

A Study to Evaluate the Effects of Tedizolid Phosphate on the Pharmacokinetics and Safety of Midazolam and Rosuvastatin (MK-1986-004)

The purpose of this study is to assess the effect of steady-state tedizolid phosphate on the single-dose pharmacokinetics of midazolam and rosuvastatin in healthy, adult participants.

Lead sponsor: Merck Sharp & Dohme LLC•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Merck Sharp & Dohme LLC

Age

19 - 55 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•healthy, adult males or females (women of non-childbearing potential)
•continuous non-smokers who have not used nicotine-containing products for the previous 3 months

Exclusion Criteria

•mentally or legally incapacitated or has significant emotional problems
•history or presence of clinically significant medical or psychiatric condition or disease
•history or presence of alcoholism or drug abuse within the past 2 years
•female participants who are pregnant, lactating, or of childbearing potential
•donated blood or had significant blood loss within 56 days prior to first dose of study drug
•plasma donation within 7 days prior to first dose of study drug

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: August 24, 2015Terms

Trial snapshot

StatusCOMPLETED

PhasePHASE1

Enrollment18

Start dateJun 2015

Last updatedAug 24, 2015

Condition

Skin Diseases, Bacterial

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: August 24, 2015Data synced to Clareo: July 13, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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