Vitamin D Plasma Level and Its Role in Headache

To date there are conflicting data concerning a correlation between plasma vitamin D levels and headache. The aim of this study was to evaluate plasma vitamin D levels in patients with headache admitted to the Center of Headache of Pugliese Ciaccio Hospital.

Several papers suggest that inflammation is able to induces both headache and low levels of vitamin D. However, to date a correlation between plasma vitamin D levels and headache has not been demonstrated. Recently we documented that low levels of Vitamin D are related to a low statin efficacy. In this study we will evaluate the plasma levels of vitamin D in patients with headache admitted to the Center of Headache of Pugliese Ciaccio Hospital. Moreover it will be also evaluated: * the correlation between efficacy and safety of drugs used in headache treatment and plasma vitamin D levels. * the role of vitamin D supplementation on both headache symptoms and drug effects. Plasma vitamin D levels in patients with headache will be evaluated respect to patients without headache.