Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Washington University School of Medicine
Age
18–55
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
BMI 21.0-24.9 kg/m²
Weight stable (+/- 2% for at least 3 months before enrollment)
Two or more of the following: IHTG content ≥5.6%, HOMA- IR index ≥ 2.5, HbA1C ≥ 5.7%, 2-hr OGTT plasma glucose concentration ≥ 140 mg/dl, fasting plasma glucose concentration ≥ 100 mg/dl.
You may not be if
Women who are pregnant or breastfeeding
Evidence of significant organ system dysfunction or disease (e.g., diabetes, chronic kidney disease, advanced heart disease, etc.)
Men who consume \>21 units (e.g., glass of wine or bottle of beer) of alcohol per week and women who consume \>14 units of alcohol per week
Use of dietary supplements or medications known to affect metabolism
Eating disorder (assessed by using the Eating Disorder Examination Questionnaire \[EDE-Q\])
Participation in structured endurance or resistance exercise program \>150 min/week
Use of tobacco products
Unable or unwilling to follow the study protocol or the research team believes that for any reason the volunteer is not an appropriate candidate for this study, including non-compliance with screening appointments or previous appointments/contact arrangements
Individuals that take Coumadin or similar anticoagulants
Use of antibiotics in last 60 days
Previous bariatric surgery
Cancer or cancer that has been in remission for \<5 years
Major psychiatric illness
Clareo Health | Effect of Moderate Weight Loss in Metabolically Abnormal Lean Subjects
