Comparison of Immunization Schedules of Inactivated Hepatitis A Vaccine and Combined Hepatitis A and Hepatitis B Vaccine

Exclusion Criteria

• •History of allergy to vaccine(s), or history of serious adverse reaction to vaccination, such as urticaria, dyspnea, angioneurotic edema, or abdominal pain;
• •Autoimmune disease or immunodeficiency;
• •Any acute disease that made the conditions of the person unsuitable for vaccination
• •Administration of any live attenuated vaccine within 14 days prior to the injection;
• •Administration of any subunit vaccine or inactivated vaccine within 7 days prior to the injection;
• •Administration of treatment of immunosuppressants (e.g., corticosteroid) within 1 month prior to the injection, or planning for such treatment during this study;
• •Body temperature \> 37.0 °C before injection;
• •Based on the evaluation of the investigator, there was any other factor that indicating the person was unsuitable for this study;
• •Any acute infectious disease, body temperature \> 38.5 °C or acute attacks of chronic diseases within 3 days prior to the second injection;
• •Administration of blood product or other investigational drug during this study;
• •Occurrence of adverse event at grade 3 or higher and the event was related to the first injection;
• •The investigator or the Ethic Committee decided that the subject should be excluded;