Arthritis, lupus and other systemic auto-immune diseases

Regional or persistent pain that could interfere with assessment of fibromyalgia pain

Bipolar and psychotic disorders

Increased risk of suicide

Significant clinical (cardiac, systemic infection, systemic corticosteroid requirement, drug/alcohol abuse) or laboratory abnormalities.

Inability to wash-out specific medications (ask PI)

Known hypersensitivity to cyclobenzaprine

Others: seizure disorders, severe/untreated sleep apnea, BMI\>40

A Study to Evaluate eFFIcacy and Safety of Sublingual TNX-102 SL Tablet Taken at Bedtime in Patients With fibRoMyalgia