Hypertension, diabetes, or heart failure by standard clinical criteria

Elevated B-type Natruiretic Peptide level (\>100 pg/ml)

Left Ventricular Ejection Fraction \< 50%

Wheelchair bound

Cardiac rhythm disorder, specifically: rhythm other than sinus, Supraventricular Tachycardia, atrial fibrillation, ventricular tachycardia

Continuous ventilatory support

Liver disease

Renal impairment

Maximum voluntary contraction of less than 20 kg or greater than 40 kg

Ventilation Devices (Continuous Positive Airway Pressure (CPAP), Bilevel Positive Airway Pressure (BiPAP))

Sodium Nitrate for Muscular Dystrophy