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TERMINATEDPhase 2NCT02434549

Botulinum Toxin-A as a Treatment for Chronic Muscle-Related Pain in Adults With Spastic Cerebral Palsy: a Randomized Controlled Trial

The purpose of this double-blinded, placebo-controlled study is to test if treatment with Botulinum toxin-A is effective in reducing chronic muscle-related pain in adults with spastic cerebral palsy.

Lead sponsor: Kristina Tedroff•2 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Kristina Tedroff

Collaborators

Danderyd Hospital
Karolinska University Hospital

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Age ≥ 18 years.
•Spastic Cerebral Palsy.
•Chronic pain, related to spastic muscle. Chronic pain defined as: 1)Recurring regional pain for at least three months AND 2)Pain intensity on average for the last 24 hours ≥3 on Numerical Rating Scale.
•Signed Informed consent.

Exclusion Criteria

•Allergy/hypersensitivity to Dysport® or any of its components.
•Pregnancy.
•Women who breastfeed their children.
•Treatment with Botulinum toxin-A within the last five months.
•If there has been dose changes in any muscle-tone altering medication within two weeks of Visit 1.
•A clear degenerative cause behind the pain as elucidated by the clinical examination (e.g. history of osteoarthritis).
•Intellectual disability and/or communication impairment that disable the individual from answering the questionnaires and giving informed consent.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: October 9, 2018Terms

Trial snapshot

StatusTERMINATED

PhasePHASE2

Enrollment16

Start dateAug 2015

Last updatedOct 9, 2018

Condition

Pain Cerebral Palsy, Spastic

Locations shown

Department of Rehabilitation Medicine at Danderyd Hospital AB

Danderyd

Astrid Lindgren's Children's Hospital at Karolinska University Hospital

Stockholm

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: October 9, 2018Data synced to Clareo: July 13, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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