Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Biogen
Age
18–58
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Onset of SPMS at least 1 to 2 years prior to randomization. SPMS is defined as relapsing-remitting disease followed by progression of disability independent of or not explained by relapses.
Have documented confirmed evidence of disease progression independent of clinical relapses over the 1 year prior to randomization.
Have an Expanded Disability Status Scale score of 3.0 to 6.5, inclusive.
Have a Multiple Sclerosis (MS) Severity Score of 4 or higher.
You may not be if
Have a diagnosis of relapsing remitting multiple sclerosis or primary progressive MS as defined by the revised McDonald criteria.
Had a recent clinical relapse (within 3 months) prior to randomization.
Uncontrolled intercurrent illness including, but not limited to: ongoing or active infection; symptomatic congestive heart failure; unstable angina pectoris; cardiac arrhythmia; serious or acute liver, kidney, or bone marrow dysfunction; uncontrolled diabetes; serious or acute psychiatric illness that would limit compliance with study requirements.
Clareo Health | BG00012 and Delay of Disability Progression in Secondary Progressive Multiple Sclerosis
