Impact of Everolimus on HIV Persistence Post Kidney or Liver Transplant

Exclusion Criteria

• •1. Pregnant, breastfeeding, or unwilling to practice birth control during participation in the study.
• •2. Presence of a condition or abnormality that in the opinion of the Investigator would compromise the safety of the patient or the quality of the data.
• •3. Patients who are intending to modify antiretroviral therapy in the next 6 months for any reason.
• •4. Serious illness requiring hospitalization or parenteral antibiotics within preceding 3 months.
• •5. A screening hemoglobin below 11.5 g/dL.
• •6. A screening TSH consistent with hypothyroidism.
• •7. Significant renal disease (eGFR \< 60 ml/min) or acute nephritis
• •8. Clinically active hepatitis as evidenced by clinical jaundice or Grade 2 or higher liver function test abnormalities.
• •9. Hepatic cirrhosis or decompensated chronic liver disease.
• •10. Concurrent treatment with immunomodulatory drugs, such an interferon-alpha, or exposure to any immunomodulatory drug in past 16 weeks (outside of standard immunosuppression).