1. Have a congenitally lethal condition (e.g. Trisomy 13)

2. Have clinically severe bleeding not able to be managed with routine measures

3. Have evidence of a viral hepatitis or primary liver disease as the etiology of their cholestasis

4. Have other health problems such that survival is extremely unlikely even if cholestasis improves

5. Known allergy to eggs or fish products

6. Receiving IV Fish oil

7. Phenobarbital therapy at enrollment

Enteral Fish Oil is Superior to Ursodeoxycholic Acid (UDCA) and Placebo for the Treatment of Cholestasis in Infants