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At least 20 psoriasis patients will be compared to at least 20 participants without psoriasis Bacterial genomic DNA will be extracted from stool samples of participants. The intestinal bacterial populations will be compared in order to examine whether there are differences between the groups.
Intestinal bacterial population has a significant influence on health and sickness conditions. It affects the development and the function of the immune system (Th2, Th1 or Th17) by bacterial protein expression and by the composition of the bacterial population. Psoriasis is an immune related dermal disease. The trigger for this disease is currently unknown but, it is possible that intestinal bacteria are a factor in its development. Study design: Participants will be divided into 3 groups: * Psoriasis patients treated with topical medications * Psoriasis patients treated with IV or sub-cutaneous medications (e.g biological medications) * Healthy participants (control group) Bacterial genomic DNA will be extracted from stool samples of participants. The intestinal bacterial populations will be compared in order to examine whether there are differences between the groups.
Age
18 - 80 years
Sex
ALL
Healthy Volunteers
Yes
Start Date
May 14, 2015
Primary Completion Date
January 6, 2019
Completion Date
February 18, 2019
Last Updated
September 25, 2019
46
ACTUAL participants
Lead Sponsor
Assuta Hospital Systems
Collaborators
NCT07449234
NCT07116967
NCT07250802
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
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