Infants scheduled for laser eye surgery on the day of the examination

Infants with intraventricular hemorrhage ≥ grade 3 (Papile classification) diagnosed by head ultrasound

Infants receiving the following medications: morphine, fentanyl, methadone, midazolam, lorazepam, muscle relaxants, phenobarbital, phenytoin, levetiracetam

Renal injury defined with plasma creatinine \> 1.5 mg/dL

Severe cyanotic congenital heart disease

Unstable respiratory distress (hypoxemia PaO2 \< 50 mm Hg or SpO2 \< 90%)

Pain and Stress Assessment and ROP Screening

What this study is about