The Efficacy and Safety Study of High Dose Donepezil in Parkinson's Disease With Dementia

Exclusion Criteria

• •Patients who cannot be performed neuropsychiatric test because of hearing and visual difficulty
• •Patients who have taken medicine affecting cognitive function such as anticholinergic drug and memantine -Patients diagnosed as dementia with Lewy body and vascular dementia-
• •Patients who have history of neurosyphilis, head trauma, encephalitis or other movement disorders
• •Patients who have psychiatric disease
• •Except patients who are stable state under antidepressant or atypical neuroleptics
• •Patients with child-bearing periods
• •Patients who have severe liver or kidney disease necessary for aggressive treatment
• •Patients who have gastrointestinal disease needed for treatment
• •Patients who cannot taken tablet per oral
• •Patients who are participated in other clinical trial except observational study