Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Arizona
Subjects will randomly receive either dexamethasone or placebo and begin the study medication during the midpoint of their radiation treatment. Study medication will be taken for 14 straight days then stopped. Fatigue and quality of life will be measured weekly with short patient completed surveys. The number of breaks taken during radiation treatment will also be tracked. For safety, blood sugar levels will be checked with finger stick blood draws because dexamethasone is known to cause these levels to increase. Study participation will be approximately 3 months.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
confirmation of head \& neck cancer (stage I-IV) or non-small cell lung cancer (stage II \& III)
Undergoing treatment with either radiation alone or in combination with chemotherapy
Normal cognition and willingness to complete fatigue and quality of life forms, patient observation form, and pill diary
You may not be if
Hypersensitivity to dexamethasone or corticosteroids or Equal sugar substitute
Corticosteroid within the past 30 days prior to study enrollment for greater than one week duration
Planned Stereotactic Body Radiation Therapy (SBRT)
Active psychosis
Current pregnancy
Active peptic ulcer disease or evidence of gastrointestinal bleed
Current active tuberculosis or systemic fungal infection
Previous diagnosis of diabetes mellitus
Acute febrile illness
Known human immunodeficiency virus or acquired immunodeficiency syndrome
Major surgery within two weeks of study enrollment of which the patient has not recovered
Psychostimulant use in the past 30 days prior to registration
