About Pricing FAQs Blog

Loading clinical trials...

Your health journey, clearly organized.

Find Clinical Trials →

Legal

Privacy Policy
Terms of Service

© 2026 Clareo Health. All rights reserved.

Study of EBI-005 in Dry Eye Disease (DED) | Clinical Trials | Clareo Health

Back to clinical trial search

UNKNOWNPhase 3NCT02405039

Study of EBI-005 in Dry Eye Disease (DED)

This is a randomized, double masked study designed to evaluate the safety of EBI-005 5 mg/mL topical ophthalmic solution given three times daily (TID) compared to vehicle-control over a one year perio...

Lead sponsor: Eleven Biotherapeutics•12 U.S. locations•View source on ClinicalTrials.gov

Clareo plain-language summary

What this study is about

Generating AI summary...

Clareo turns complex medical information into clear understanding you can use.

Bring this clarity to your next appointment.

Keep all your medical notes and next steps in one place.

Sponsors

Lead Sponsor

Eleven Biotherapeutics

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•1. Have a history of dry eye disease (DED) in both eyes supported by a previous clinical diagnosis or have a self-reported history of subjective complaints for at least 6 months prior to Visit 1
•2. Are willing and able to follow instructions and can be present for the required study visits for the duration of the study

Exclusion Criteria

•1. Have an ocular condition that could confound study assessments (ocular infection, herpetic or neurotrophic keratitis, Steven-Johnson Syndrome, etc)
•2. Have had penetrating intraocular surgery within 12 months prior to Visit 1
•3. Be unwilling to comply with the study requirements

Related studies

RECRUITINGPhase 4

A Non-interventional Study to Evaluate the Anti-inflammatory Effects and the Clinical Efficacy of Topical Water Free Cyclosporin 0.1% Eye Drops in Patients With Dry Eye Disease and Associated Ocular Surface Inflammation Non-responding to Artificial Tears: the FOCUS Study

NCT07463950 · Dry Eye Disease (DED)

A Study on the Correlation Between Tear Iron Levels and the Severity of Dry Eye Disease.

NCT07363824 · Dry Eye Disease, Iron

RECRUITINGPhase 4

Supplementary Kelulut Honey Therapy in Juvenile Open-Angle Glaucoma: Effects on IL-6, RNFL and Dry Eye

NCT07396441 · Juvenile Open Angle Glaucoma, Dry Eye Disease (DED), and more

Efficacy and Safety of BUFY01 Versus SVS20 in the Treatment of Dry Eye Disease

NCT05865379 · Dry Eye Disease

Efficacy and Safety of BUFY02 Versus TRB02 in the Treatment of Dry Eye Disease

NCT05865457 · Dry Eye Disease

View all related studies →

Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: June 4, 2015Terms

Trial snapshot

StatusUNKNOWN

PhasePHASE3

Enrollment188

Start dateApr 2015

Last updatedJun 4, 2015

Condition

Locations shown

Birmingham, Alabama

Newport Beach, California

Hamden, Connecticut

For caregivers

Use Clareo to keep notes, questions, trial details, and next steps organized before and after appointments.

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 4, 2015Data synced to Clareo: May 10, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions