Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Maryland, Baltimore
Age
18–64
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Eligible and recommended for clozapine treatment (e.g. treatment resistant schizophrenia, schizoaffective disorder, bipolar disorder, other psychotic disorder, delusional disorder, hostility, other documented rationale)
Male or Female
African Ancestry (African, African-American or African-Caribbean). This population will make up the majority of the study. However, there are cases of BEN in individuals of Middle Eastern, Caucasian, and other ethnicity. The investigators will accept these patients as they may have unknown African ancestry and genotyping will be important.
Age: 18 to 64 years.
History of a low absolute neutrophil count (ANC\<2500 cells/mm3 in past 24 months)
Documented ability to sign informed consent. This is a score of ≥10/12 on ESC.
Effective birth control if of child bearing potential
Medical condition whose pathology or treatment would likely alter the presentation or treatment of schizophrenia or significantly increase the risks associated with the proposed protocol.
Medical condition affecting patient's ability to mount an immune response
Current bacterial or viral infection\*
Sickle cell anemia
Positive for bacteria in urine culture\*
Temperature \> 37.5 º Celsius, 99.5 º Fahrenheit\*
