Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Gilead Sciences
Age
18–70
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
All individuals:
* Screening laboratory values within defined thresholds for group
* Use of two effective contraception methods if female of childbearing potential or sexually active male
For individuals with moderate hepatic impairment:
* Diagnosis of chronic (\> 6 months) hepatic impairment
* Score on the Child-Pugh-Turcotte (CPT) scale of 7-9 at screening (Child Pugh Class B).
For individuals with severe hepatic impairment:
* Diagnosis of chronic (\> 6 months) hepatic impairment
* Score on the CPT scale of 10-15 at screening (Child Pugh Class C)
For individuals with normal hepatic function:
* Hepatitis C Virus (HCV) antibody and hepatitis B surface antigen negative
You may not be if
All individuals:
* Pregnant or nursing female or male with pregnant female partner
* HIV infection
* History of clinically significant illness or any other medical disorder that may interfere with the individual's treatment, assessment or compliance with the protocol
For individuals with moderate or severe hepatic impairment:
* Active HCV infection
* Current hepatic encephalopathy
* Variceal bleeding in the last 6 months unless banded
* Prior placement of a portosystemic shunt
* History of hepatorenal or hepatopulmonary syndrome
* Spontaneous bacterial peritonitis currently or within the last 6 months
* Hospitalization within the last 2 months related to cirrhosis
