Finding studies
Finding studies
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Lead
Priyanka Sharma
With
Breast cancer is the most common cancer and the second leading cause of cancer related death in American women. Despite recent improvement in the treatment of breast cancer, 40,000 women per year still die in the U.S.as a result of breast cancer. Once the disease has gotten worse (progressed) after standard chemotherapy treatments, there are limited treatment options and the likelihood for patients to recover is very small. The study will be done in two phases: Phase I will determine the highest dose of romidepsin that is safe and tolerable to take in combination with cisplatin. Phase II will determine if taking romidepsin (at the dose determined in Phase I) in combination with cisplatin and nivolumab is safe and effective in treating patients with breast cancer. Phase I will complete before Phase II begins.
Age
18–any
Sex
FEMALE
Healthy volunteers
Not accepted