History of allergic reaction or other adverse event while using varenicline

Used a smoking cessation aid/medicine in past 1 month (including e-cigs)

Currently pregnant or nursing

Does not have a mobile phone that can send and receive text messages or unwilling to receive study texts

Uncontrolled serious mental illness or substance abuse or inpatient treatment for these in the past 6 months

Uses non-cigarette tobacco products and does not plan to quit all tobacco.

Has a history of kidney problems or receives dialysis

Had any thoughts that they would be better off dead or of deliberate self-harm in the prior 4 weeks

Had a heart attack in the past 4 weeks

Mental conditions that would prohibit the participant from completing the protocol

Penn State TXT2Quit Study