Dynamic Respiratory Muscle Function in Late-Onset Pompe Disease

Exclusion Criteria

• •Pre-existing obstructive lung disease or asthma
• •Forced vital capacity (FVC) \<30% or \>80% of age/gender predicted values
• •Inability to travel to the study site
• •Requirement for positive pressure ventilator support when awake and upright
• •Participation in longitudinal studies that may independently alter lung function
• •Presence of any other chronic medical condition that, in the opinion of the investigator, would make the subject unsuitable for the study