Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Zurich
With
ETH Zurich
Age
Any age
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Dementia expert considers an Amyloid-scan appropriate according to Amyloid-imaging task force criteria (AIT) after conference with an Amyloid-PET expert
Preambles of the AIT-Criteria are fulfilled
1. A cognitive complaint with objectively confirmed impairment
2. AD as a possible diagnosis, but when the diagnosis is uncertain after a comprehensive evaluation by a dementia expert
3. When knowledge of the presence or absence of Abeta pathology is expected to increase diagnostic certainty and alter Management
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1. Patients with persistent or progressive unexplained MCI
2. Patients satisfying core clinical criteria for possible AD because of unclear clinical presentation, either an atypical clinical course or an etiologically mixed presentation
3. Patients with progressive dementia and atypically early age of onset (65 years or less in age)
4. other situations where preambles of AIT-Criteria are fulfilled
Diagnosis was established in a memory clinic or by an experienced physician in dementia diagnostics
The diagnostic procedures comprise in minimum MRI, neuropsychology, routine blood test for exclusion of symptomatic causes
MMSE \>15
Competency to consent
Trial partner willing to support study physician
Written informed consent by both patient and trial partner
Understanding of German language
Treating physician willing to collaborate with the study team
You may not be if
Cognitive impairment which can be attributed to another underlying medical condition that renders a possibility of Alzheimer's disease very unlikely (thus violating preamble B)
Clinically significant Depression (decided upon clinical assessment)
1. Allergy to Flutemetamol or any of the excipients of the solution for injections
2. History of severe allergic reactions to drugs or allergens
