Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Ohio State University
With
University of Wisconsin, Madison
Massachusetts General Hospital
University Hospitals Cleveland Medical Center
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patients with migraines related to a trigger site at the location of a branch of a cranial nerve (frontal, temporal, occipital)
Patients with chronic migraine (≥15 days per month) as dictated by the FDA indication for botulinum, and as diagnosed by a board-certified neurologist
Patients with episodic migraines
* Those patients are included because there is no consensus whether surgical decompression is effective for chronic migraines only, or for chronic and episodic migraines. One of the goals of this trial is to determine this.
Patients who respond to diagnostic botulinum toxin injection or to a diagnostic anesthetic block
Patients who have failed 2 of 3 classes of preventative migraine medications
You may not be if
Patients deemed by the authors or the neurologist to not have migraine headaches, but an alternative diagnosis
Patients with systemic conditions that make them poor candidates for surgery (coronary artery disease, uncontrolled diabetes mellitus, etc…)
Patients with migraines related to inferior turbinate hypertrophy or septal deviation
Patients with a frontal, temporal or occipital trigger point who do not respond to a diagnostic botulinum toxin injection or to a diagnostic anesthetic block
Hypersensitivity to any botulinum toxin preparation or to any of the components in the formulation
Infection at the proposed injection site for botulinum
Patients with trigger points at minor trigger sites (lesser occipital nerve, third occipital nerve)
