Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Maastricht University Medical Center
With
UMC Utrecht
Leiden University Medical Center
University Medical Center Groningen
Amsterdam UMC, location VUmc
Dutch Heart Foundation
Age
18–any
Sex
FEMALE
Healthy volunteers
Accepted
You may be eligible if
Cases
Women aged ≥ 18 years
½ till 30 years after the complicated pregnancy
Experienced PE in any pregnancy. PE defined as hypertension (systolic BP ≥ 140 mmHg and/or diastolic BP ≥ 90 mmHg) developed after 20 weeks of pregnancy with the development of proteinuria (≥ 300 mg/ 24 hours).
Women who had their last delivery at least 6 months ago.
Controls
Women aged ≥ 18 years
½ till 30 years after the pregnancy that matches the sequence number of pregnancy of the specifically matched case.
Experienced pregnancies that were not complicated by foetal or maternal placental syndrome (pregnancy induced hypertension, preeclampsia, HELLP-syndrome).
Women who had their last pregnancy at least 6 months ago.
Women with a negative family history for PE (mother and sisters did not experience PE).
You may not be if
A potential subject who meets any of the following criteria will be excluded from participation in this study:
Cases
Women with auto-immune diseases prior to the complicated pregnancy.
Chronic hypertension prior to the complicated pregnancy.
Renal disease prior to the complicated pregnancy.
Pregnant women
Women who do not want to be informed about the results of the tests, or women who do not want their general practitioner and specialist(s) to be informed about the test results.
Control group:
Women with auto-immune diseases
Chronic hypertension prior to the matched pregnancy.
Women with IUGR in the matching pregnancy (p\<10)
Solutio placentae in the matching pregnancy
Pregnant women
Women who do not want to be informed about the results of the tests, or women who do not want their general practitioner and specialist(s) to be informed about the test results.
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