Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Medical University of Vienna
28 days of 6 grams Taurine versus Placebo (randomization 1:1).
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patients (male and female) aged older than 18 years with advanced liver cirrhosis (Child's Grade B and Child's Grade C), regardless of the disease origin (viral, alcoholic, idiopathic), who are scheduled for hepatic hemodynamic investigation
Negative pregnancy test of women with childbearing potential
Patient without beta blocker therapy: due to: intolerance of the medication, preexisting contraindication against beta blocker therapy, endoscopic band ligation as prophylaxis
You may not be if
History of variceal bleeding without endoscopic band ligation
History of endoscopically diagnosed large varices with red spots without previous bleeding and without endoscopic band ligation
HVPG \< 10 mmHg
HVPG \> 20 mmHg and varices, unless ligated and treated in an eradication program within 6 months
Beta Blocker therapy
History of hypersensitivity to the trial drugs and contrast agent or to drugs with similar chemical structure
Treatment with vasoactive or non-steroidal anti-inflammatory drugs or systematic antibiotics one week before the study
Cardiac, renal or respiratory failure
Previous surgical or transjugular intrahepatic portosystemic shunt
