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Effects of Bile Acids on GLP-1 Secretion After Roux-en-Y Gastric Bypass | Clinical Trials | Clareo Health

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Effects of Bile Acids on GLP-1 Secretion After Roux-en-Y Gastric Bypass

Effects of Ursodeoxycholic Acid and Chenodeoxycholic Acid on GLP-1 Secretion After Roux-en-Y Gastric Bypass

NCT02340247•Hvidovre University Hospital

View on ClinicalTrials.gov

Summary

The purpose of this study is to examine the effects of bile acids on GLP-1 secretion after Roux-en-Y gastric bypass.

Eligibility

Age

All ages

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Uncomplicated RYGB performed minimum 3 months prior to the study.
•Fasting plasma glucose \< 7.0mM, HbA1c \< 48mmol/mol 3 months after RYGB.

Exclusion Criteria

•Fasting plasma glucose \> 7.0mM, HbA1c \> 48mmol/mol 3 months after RYGB.
•Dysregulated hypothyroidism, use of antithyroid treatment.
•Late diabetic complications as retinopathy, renal insufficiency, neuropathy or previous pancreatitis.
•Complications to RYGB: Documented reactive hypoglycaemia, severe dumping (vomiting, diarrhea, severe abdominal pain after food intake).

Locations (1)

Hvidovre University Hospital

Hvidovre, Denmark

Key Dates

Start Date

November 1, 2014

Primary Completion Date

April 1, 2015

Last Updated

June 30, 2016

Enrollment

ACTUAL participants

Conditions

Severe Obesity

Interventions

Water

OTHER

Ursodeoxycholic Acid

DRUG

Chenodeoxycholic Acid

DRUG

Obesity Cohort Bichat Louis Mourier

NCT03538210

Severe ObesityBariatric Surgery+1 more

View study

ACTIVE_NOT_RECRUITINGNA

Bypass Equipoise Sleeve Trial (BEST)

NCT02767505

Severe Obesity

View study

COMPLETED

Longitudinal Retrospective Analysis of Prospectively Collected Data for Outcomes After Primary Sleeve Gastrectomy (N=20 000) in the Swedish National Quality Registry SOReg (Scandinavian Obesity Surgery Registry)

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 30, 2016Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Effects of Bile Acids on GLP-1 Secretion After Roux-en-Y Gastric Bypass

Inclusion Criteria

Exclusion Criteria

Obesity Cohort Bichat Louis Mourier

Bypass Equipoise Sleeve Trial (BEST)

Longitudinal Retrospective Analysis of Prospectively Collected Data for Outcomes After Primary Sleeve Gastrectomy (N=20 000) in the Swedish National Quality Registry SOReg (Scandinavian Obesity Surgery Registry)

Pigeon Peas (Cajanus Cajan) : a Natural Anti-inflammatory Facilitating Weight Loss in Obese Patients Returning to Sport?

Hospital Discharge Following Bariatric Surgery by Telepresence Robot

Gut Hormones as Mediators of Different Weight Loss Responses After Roux-en-Y Gastric Bypass