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Ultrasound Guided Intermediate Cervical Plexus Block -Randomized Evaluation Concerning the Significance of Additional Perivascular Local Anesthetic Infiltration
For ultrasound guided intermediate cervical plexus block this randomized comparison is testing the hypothesis, that an additional perivascular infiltration is associated with increased block quality.
The innervation of the neck is complex and involves the cervical and the brachial plexus as well as cranial nerves. So is the wall of the carotid arteries innervated by vagal and glossopharyngeal nerve as well as the sympathetic trunk. When carotid surgery was performed under regional anesthesia, so additional infiltration of local anesthetic by the surgeon was common, particularly during preparation of the carotid arteries. Introduction of ultrasound guidance made it possible to guide the needle directly to the vascular wall. But this procedure is considered very demanding, because of guiding the needle in an anatomical region with artifacts (because of calcification), sudden movements (e.g. because of swallowing) and compromised coagulation (antithrombotic medication). On the other side there are no clinical data proving the benefit of an additional perivascular infiltration with local anesthetic. Therefore, this investigation is testing the hypothesis, that an additional perivascular infiltration is associated with increased block quality.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Start Date
September 1, 2013
Primary Completion Date
December 1, 2014
Completion Date
December 1, 2014
Last Updated
March 23, 2015
40
ACTUAL participants
intermediate cervical plexus block ropivacaine
DRUG
pericarotidal infiltration (active comparator) ropivacaine
DRUG
jugular infiltration prilocaine
DRUG
pericarotidal infiltration (placebo comparator) saline
DRUG
Lead Sponsor
Helios Research Center
NCT07412249
NCT07057297
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT06315153