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Effect of Portal Vein Thrombosis on the Prognosis of Liver Cirrhosis: A Single-center, Prospective, Cohort Study
The prevalence of portal vein thrombosis (PVT) in patients with liver cirrhosis is 5-20%. Current evidence regarding the effect of portal vein thrombosis on the prognosis of cirrhotic patients remains under debate. Considering that PVT potentially elevates the portal pressure and thereby increase the risk of variceal bleeding, we focus on the patients with high-risk varices and variceal bleeding as the study population. Thus, the main goals are to analyze the effect of PVT on the incidence of first variceal bleeding in patients without any prior bleeding history but with high-risk varices, the incidence of recurrent variceal bleeding in patients with a history of variceal bleeding, and the treatment failure rate of variceal bleeding in patients with acute variceal bleeding. Certainly, the survival is also observed in all patients.
Age
All ages
Sex
ALL
Healthy Volunteers
No
Department of Gastroenterology, General Hospital of Shenyang Military Area
Shenyang, Liaoning, China
Start Date
December 1, 2014
Primary Completion Date
December 1, 2022
Completion Date
December 1, 2022
Last Updated
February 24, 2023
475
ACTUAL participants
Somatostatin and its analogs
DRUG
Endoscopic sclerotherapy, endoscopic variceal ligation, endoscopic tissue glue injection
PROCEDURE
Lead Sponsor
General Hospital of Shenyang Military Region
NCT06169592
NCT07275554
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