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Keep this study
Lead
University of Zurich
With
Kantonsspital Winterthur KSW
Triemli Hospital
Cantonal Hospital of St. Gallen
This prospective, randomized study will be conducted over a 36-month period to investigate whether commonly used anesthetics (volatile versus intravenous) have an effect on the changes or occurrence of CTC in patients suffering from primary pancreatic cancer undergoing curative surgery. The specific research question is if there are changes of the CTC count in the postoperative phase in the desflurane group (intervention) compared to the propofol one (control). A secondary question is if these changes can be correlated to tumor outcome.
Age
18–85
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age 18 to 85
ASA I-III ( American Society of Anesthesiologists)
Resectable pancreatic adenocarcinoma
Primary surgery
No neoadjuvant therapy
Written informed consent
You may not be if
Metastatic disease
Other than primary surgery (recurrence, reconstruction)
Pre-operative chemotherapy
Chronic opioid use
Known hypersensitivity or suspected allergy to propofol, soya or egg proteins
Known hypersensitivity to volatile anaesthetics (malignant hyperthermia)
Pregnancy
Breast feeding
Enrolment in any other clinical trial during the course of this trial, 30 days prior to its beginning or 30 days after its completion
