Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University Hospitals Cleveland Medical Center
With
National Psoriasis Foundation
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Subjects ages 18-65 years old
Diagnosis of moderate-to-severe plaque psoriasis
Plaque affects ≥ 10% of subject's body surface area (BSA)
Subjects prescribed one of the following standard-of-care treatments for their psoriasis: Ustekinumab, Methotrexate, Etanercept, Adalimumab, Narrow Band UVB (311nm), Excimer Laser Treatment (308nm), or Acitretin
Subjects willing to complete a Washout Period prior to Visit 1 (only for subjects currently on a psoriasis treatment):
* Discontinue systemic therapies for at least 4 weeks
* Discontinue topical therapies for at least 2 weeks
* Discontinue phototherapies for at least 2 weeks
You may not be if
Subjects who are currently on a psoriasis treatment and unwilling to go through the washout-period
Subjects with a critical illness or who are immunocompromised
Weight is 400lbs or greater
Subjects who are currently pregnant or breastfeeding
Subjects who have metal implants
Subjects who have a pacemaker, stent, or artificial heart valve
History of clinically significant hematological, renal or liver disease
Patients with known co-morbidities that raise biomarkers such as:
* History of myocardial infarction (MI)
* History of cerebrovascular accident (CVA)
* Significant atherosclerosis (defined as the presence of any carotid plaque; or carotid intimal media thickness (cIMT) \>75th percentile for age; or the presence of coronary artery calcium score\>100)
