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Airway Response to Repeat Allergen Challenge and the Effect of Ibuprofen in Mild Atopic Asthma | Clinical Trials | Clareo Health

COMPLETEDNA

Airway Response to Repeat Allergen Challenge and the Effect of Ibuprofen in Mild Atopic Asthma

Assessment of Repeated Allergen Challenge and the Effects of Ibuprofen on the Inflammatory Process

NCT02327234•University of Saskatchewan

View on ClinicalTrials.gov

Summary

The study will assess airway responses in mild atopic asthmatics undergoing repeat allergen challenge testing and will investigate whether ibuprofen changes the response.

Eligibility

Age

18 - 70 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•diagnosis of mild asthma, currently well controlled requiring only a bronchodilator (e.g. salbutamol) as needed and infrequently
•has allergies that trigger asthma
•responds to methacholine challenge at 16mg/ml or less
•has FEV1 \> 69.5% predicted

Exclusion Criteria

•respiratory illness within 4 weeks
•other medical condition assessed by the principal investigator that would put the participant at risk or influence the integrity of the data
•pregnant or lactating females
•hypersensitivity to ibuprofen

Locations (1)

University of Saskatchewan

Saskatoon, Saskatchewan, Canada

Key Dates

Start Date

December 1, 2014

Primary Completion Date

April 1, 2015

Completion Date

April 1, 2015

Last Updated

April 20, 2016

Enrollment

ACTUAL participants

Conditions

Atopic Asthma

Interventions

ibuprofen

DRUG

Placebo

DRUG

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NOT_YET_RECRUITINGNA

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: April 20, 2016Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Airway Response to Repeat Allergen Challenge and the Effect of Ibuprofen in Mild Atopic Asthma

Inclusion Criteria

Exclusion Criteria

A Study To Evaluate The Efficacy, Safety, Pharmacokinetics, And Pharmacodynamic Effects Of GDC-6599 In Patients With Chronic Cough

Vibroacoustic Therapy With Oscillating Positive Expiratory Pressure in the Treatment of Nasal Congestion

A Double Masked, Placebo Controlled, Single Center, Randomized Clinical Trial to Assess the Safety and Efficacy of Subjects With Mild Asthma Induced by the Bronchial Allergen Challenge (BAC)

Randomized Controlled Trial of Silymarin in Asthma

Differential Gene Expression in Lung and Peripheral Blood After Inhaled Allergen Challenge

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of ADC3680B in Subjects With Partly Controlled Atopic Asthma