Adjunctive Neurovascular Support for Wide-neck Aneurysm Embolization and Reconstruction

Exclusion Criteria

• •Unstable neurological deficit (condition worsening within the last 90 days)
• •Subarachnoid Hemorrhage (SAH) within the last 60 days
• •Irreversible bleeding disorder
• •mRS score ≥3
• •Patient has another aneurysm which, in the Investigator's opinion, will require treatment within the follow up period (365 days)
• •Platelet count \< 100 x 103 cells/mm3
• •Inability to tolerate, adverse reaction or contraindication to taking aspirin or clopidogrel
• •A history of contrast allergy that cannot be medically controlled
• •Known allergy to nickel
• •Relative contraindication to angiography (e.g., serum creatinine \> 2.5 mg/dL)
• •Woman with child-bearing potential who cannot provide a negative pregnancy test
• •Evidence of active infection
• •Other conditions of the heart, blood, brain or intracranial vessels that carry a high risk of neurologic events
• •Evidence of disease or condition expected to compromise survival or ability to complete follow-up assessments during the 365-day follow-up period
• •Extracranial stenosis greater than 50% in the parent artery requiring access to the lesion
• •Intracranial stenosis greater than 50% in the treated vessel
• •Extreme vessel tortuosity that prohibits appropriate control of the micro-guide wire and/or the PulseRider delivery wire