Effects of Nicotine-Free Hookah Smoking on Blood Flow to the Heart, Muscle and Skin

Exclusion Criteria

• •Exhaled carbon monoxide level greater than 10 ppm\* as evidence of current or recent cigarette (excluded if smoked cigarette within 12 months) or Hookah smoking (excluded if smoked Hookah within past 72 hours)
• •History of cardiopulmonary disease
• •Use of any prescription medication with exception of oral contraceptive pills
• •History of psychiatric illness
• •History of neurologic disease
• •BMI ≥ 35
• •Evidence of any of the above by physical examination, ECG or echocardiogram
• •Smoked cigarette in the past 12 months
• •History of illicit drug use
• •Pregnant
• •Any other condition(s) deemed by the physician investigators that put subjects at risk for participating in the study