Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University Hospital, Grenoble
With
National Cancer Institute, France
The project aims to study protein turnover in glioblastoma using mass spectrometry after 13C-valine incorporation. This will allow to identify proteins in circulation secreted by tumor which could be diagnostic and pronostic biomarkers in patients With High-grade Glioma.
Age
18–90
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
more or equal than 18 years old
patient affiliated to social security or similarly regime
informed consent form signed
High-grade Glioma tumor suspicion
Resective surgery indication
Hematological assessment :
* neutrophils \> 1500/mm3
* Platelet \> 150 000
* blood Creatinin normal
* alkaline Phosphatases and transaminases no more than two times normal
* Bilirubin \< 1.5 times normal
Intratumoral hemorrhage MRI detected
Treatment anticoagulant or antisludge treatments
Active Infections and non controled or medical affection or psychiatric intercurrent non treated
Evolutive cerebral oedema without corticoid response
Non controled Epilepsy without antiepileptics response
Karnofsky score \< 40%
Weight \> 100 kg
No possibility of resective surgery
You may not be if
Pregnant women and lactating mothers
Ward of court or under guardianship
Adult unable to express their consent
Person deprived of freedom by judicial or administrative decision
Person hospitalized without their consent
Person under legal protection
Precedent complete macroscopic tumor resective surgery
Clareo Health | Study of Tumor Metabolism by Isotopic Tagging in Patients With High-grade Glioma (CARBONOMIC)
