Bridge-Enhanced ACL Repair-Safety Study (BEAR Trial)

Exclusion Criteria

• •Prior surgery on affected knee
• •History of prior infection in affected knee
• •Regular use of tobacco or nicotine in any form
• •Use of corticosteroid within last 6 months
• •Ever underwent chemotherapy treatment
• •History of sickle cell disease
• •History of anaphylaxis
• •Any condition that could affect healing (Diabetes, inflammatory arthritis, etc)
• •Diagnosis of posterolateral corner injury (LCL complete tear, Biceps femoris tendon avulsion, tear of the arcuate ligament, tear of the popliteus ligament)
• •Diagnosis of Grade III medial collateral ligament injury
• •Diagnosis of complete patellar dislocation
• •ACL deemed normal on arthroscopic inspection
• •Time from injury to surgery is greater than 90 days (for Comparator group) and greater than 30 days (for Experimental group)
• •Experimental Group: Less than 50 percent of ACL remaining
• •Displaced bucket handle meniscal injury requiring repair
• •Diagnosis of full-thickness chondral injury on either condyle
• •Grade III medial collateral ligament injury