Study of Social Cognition by Morphological and Functional Imaging in Multiple Sclerosis Patients

Exclusion Criteria

• •Other progressive neurological disease;
• •psychiatric comorbidity including severe depression according to Diagnostic and Statistical Manual-IV (DSM-IV),
• •alcohol or other addiction to toxic,
• •Expanded Disability Status Scale (EDSS) \> 6; disabling visual or motor problems preventing participation to neuropsychological assessments,
• •relapse since less than one month,
• •change of disease-modifying therapy or psychotropic drug since less than one month,
• •Contra-indication to MRI (pacemakers, aneurysm clips, artificial heart valves, ear implants, metal fragments or foreign objects in the eyes, skin or body, claustrophobia) or refusing MRI
• •Illiteracy, is unable to count or to read
• •Pregnant or breastfeeding women
• •Being under guardianship
• •History of neurological disease;
• •family history of MS;
• •psychiatric comorbidity including severe depression according to DSM-IV;
• •alcohol or other toxic addiction;
• •psychotropic drugs; known cognitive complaint or neuropsychological affection;
• •Prior neuropsychological testing with the same tests less than one year
• •Contra-indication to MRI (pacemakers, aneurysm clips, artificial heart valves, ear implants, metal fragments or foreign objects in the eyes, skin or body, claustrophobia) or refusing MRI
• •Illiteracy, is unable to count or to read
• •Pregnant or breastfeeding women
• •Being under guardianship