Food Effect and Dosage Form Proportionality Study of Eslicarbazepine Acetate

Inclusion Criteria

• •Male or female subjects aged between 18 and 55 years, inclusive.
• •Subjects of body mass index (BMI, kg/m2) within the normal range \[4\], i.e., between 18.50 and 24.99, inclusive.
• •Subjects who were healthy as determined by pre-study medical history, physical examination, vital signs, and 12-lead ECG.
• •Subjects who had clinical laboratory test results clinically acceptable at screening and admission to first treatment period.
• •Subjects who had negative tests for HBsAg, anti-HCVAb and anti- HIV-1 and HIV-2 Ab at screening.
• •Subjects who had a negative screen for alcohol and drugs of abuse at screening.
• •Subjects who were non-smokers or ex-smokers who discontinued smoking at least 3 months prior to admission.
• •Subjects who were able and willing to give written informed consent.
• •(If female) She was not of childbearing potential by reason of surgery (hysterectomy or tubal ligation) or, if of childbearing potential, she used one of the following methods of contraception: intrauterine device (by the study subject) + condom (by the partner), diaphragm (by the study subject) + condom (by the partner), or spermicide (by the study subject) + condom (by the partner).
• •(If female) She had a negative urine pregnancy test at screening and admission to each treatment period.
• +16 more criteria