Males that comply with any applicable contraceptive requirements or females of non-childbearing potential

No history of active or chronic disease other than that allowed by study (hypertension, hyperlipidemia and GERD or heartburn)

Has a body mass index of 25-35 kg/m2 with a body weight of greater than 140lbs (assessed at screening)

Safety and Tolerability Study of SHP626 in Overweight and Obese Adults