Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Centre Hospitalier Departemental Vendee
Age
18–any
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
upper age to 18 years
mammary adenocarcinoma nonmetastatic and histologically proven
wait under an adjuvant or neoadjuvant chemotherapy according to the following conventional scheme: 3 cycles of F5-Fluorouracil, epirubicin and cyclophosphamide 100 (500 or 5-Fluorouracil 600 mg / m² J1, Epirubicin 100 mg / m² J1, Cyclophosphamide 500 or 600 mg / m² J1 or 3 cycles of Epiribucin and Cyclophosphamide 100) followed by 3 cycles of docetaxel, 100 mg / m², +/- trastuzumab if Her2+++
Patient with the capacity/faculties to understand a newsletter and sign an informed consent
Patient receiving social coverage
Patient who can be treated and followed in the center for a period of at least one year
WHO scale 0 or 1
You may not be if
Age below 18 years
Diseases of the scalp or whatever hair-showing against helmet or alopecia
Using pre nail resin before and per chemotherapy
mammary adenocarcinoma stage IV
Indication of docetaxel for cancer of another organ than breast
Treatment processing or programmed during chemotherapy with an innovative molecule being evaluated
Raynaud's syndrome, cold agglutinin disease, cryoglobulinemia and cryofibrinogenemia.
Uncontrolled severe arterial disease.
Presence of a device\> grade 1 neuropathy before the start of chemotherapy
Patient unable to submit the protocol followed for psychological, social, family or geographical
Patient with an incompatible underlying disease or concomitant with the inclusion in the trial, whether psychiatric or somatic
Patient trust, guardianship, under legal protection measure, deprived of freedom
Male
Criteria for non randomization (before the first course of docetaxel) :
* Presence of peripheral neuropathy\> grade 1 after the first 3 cycles of 5-Fluorouracil, epirubicin and cyclophosphamide 100.
* Presence of a nail or skin toxicity\> grade 1 after 3 cycles of 5-Fluorouracil, epirubicin and cyclophosphamide 100.
Clareo Health | Evaluation of Cryoprotection Induced Nail Toxicity Docetaxel Low Cumulative Dose
