Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
VA Office of Research and Development
Age
21–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patients on CHD undergoing three time a week therapy for more than 6 months;
Age 21 years old;
Acceptable dialysis adequacy (spKt/V \> 1.2);
A patent, well-functioning, arterio-venous dialysis access;
Ability to give informed consent;
Life expectancy greater than 6 months;
BMI \>=20 and \<=45.
You may not be if
Pregnancy;
Intolerance or allergy to the study medication (including the metabolic clamp studies);
Severe, unstable, active inflammatory disease (active infection, active connective tissue disorder), active cancer or cancer history in the prior 5 years except skin cancer, AIDS-HIV, active or history of liver disease (including hepatitis B virus and hepatitis C virus);
Hospitalization or infection within 1 month prior to the study;
Patients receiving steroids and/or other immunosuppressive agents (Prednisone \> 5 mg/day; excluding inhaled and topical steroids);
Diabetes Mellitus on insulin therapy;
Previous history of tuberculosis (TB) with or without documented adequate therapy;
Patients with recent close exposure to an individual with active TB;
Females using oral contraceptives;
Patients with New York Heart Association (NYHA) Class III or IV heart failure;
Patients with a history of angina, myocardial infarction, transient ischemic attacks, or strokes within the last 6 months.
Clareo Health | Nutrition, Inflammation and Insulin Resistance in End Stage Renal Disease-Aim 2
