Role of Bronchoscopy in Early Lung Cancer Screening of High Risk Population

Exclusion Criteria

• •Patient has dysrhythmia or cardiovascular disease that poses a risk during exercise.
• •Patient has uncontrollable hypertension (SBP \> 180mmHg).
• •Patient has severe organ dysfunction (shock, severe hepatic and renal dysfunction, massive hemorrhage of upper gastrointestine, diffuse intravascular coagulation(DIC) and massive hemoptysis,etc).
• •Patient has blood coagulation disorders (PT\>2 times the upper limit of normal(ULN) or Platelet(PLT)\<50000/ul）.
• •Patient has severe dyspnea.
• •Patient is allergic to local anesthetic.
• •Patient is unable to provide informed consent.
• •Patient is not an appropriate candidate for or is unable to tolerate flexible bronchoscopy procedures.
• •Patient has any disease or condition that interferes with completion of initial or follow-up assessments of the effectiveness endpoints.
• •Patient has demonstrated unwillingness or inability to complete screening or baseline data collection procedures.
• •Patient participated in a study of an investigational drug or device within the past 30 days prior to participation in this study, or is currently participating in another clinical study.
• •Patient has pulmonary lesions suspected to be cancer from CT images.
• •Female patient of childbearing potential has a positive result from a pregnancy test.