Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Kuopio University Hospital
The purpose of the study is to test the effects of intraoperative metoprolol on 1) anaesthetic and alagesic use 2) pain during the early postoperative period and 3) the incidence of pain and lide satisfaction up to 12 months after the surgery. Adverse effects will be recorded as safety measures.
Age
18–65
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
Elective breast surgery due to breast cancer
Voluntary
BMI ≥ 18 and ≤ 35 kg/m2
ASA 1-3
No regular use of beta-blockers or during the last 72 hours
No contraindications to beta-blockers
You may not be if
Pregnancy or breast feeding
AV-block, degree II or III
Untreated cardiac insufficiency
Sinus bradycardia, heart rate \< 45 / min or symptoms
Sick sinus syndrome
Cardiogenic shock
Severe peripheral vascular disorder
Systolic blood pressure \< 100 mmHg
Long PQ-time, \> 0,24 seconds
Known hypersensitivity to beta-blockers or the ingredients of the drug
Clareo Health | The Effect of Metoprolol on Anaesthesia, the Need for Analgesics, and Pain in Breast Cancer Patients
