Parental One-carbon Folate and Choline Nutrition Modulates Risk of Off-spring Cancer Development: Human Cohort Study

Inclusion Criteria

• •1. Healthy pregnant women aged 21-40 years with first and single fetal pregnancy
• •2. Healthy pregnant women aged 21-40 years with first and single fetal pregnancy and lineal relative had diabetes
• •3. Healthy pregnant women aged 21-40 years with first and single fetal pregnancy and lineal relative had cancer
• •4. Healthy pregnant women, who are overweight/obesity (pre-pregnancy BMI≧24 kg/m2) or her lineal relative with overweight/obesity, aged 21-40 years with first and single fetal pregnancy.